P01-009 – 2 years of colchicine IV in intractable FMF
نویسندگان
چکیده
Methods We retrospectively reviewed records of our dayhospitalization from 2007 to 2012 for patients with FMF unresponsive to oral treatment who were treated with supplemental 1mg IVC (120 min infusion) once a week. We tabulated records of clinical events: fever, number of attacks per month and CRP levels before and after at least one year of this treatment. Adverse events were also recorded, and compared with a matched control population of FMF patients only treated with oral colchicine.
منابع مشابه
P01-010 – Anti-TNF agents in intractable FMF: four cases
Introduction Familial Mediterranean Fever (FMF) is an autoinflammatory disease characterized by recurrent attacks of fever and serositis. A relation between FMF and Ankylosing Spondylitis (AS) has been suggested in small cohort studies, although there is no consensus regarding the role of HLA B27. Colchicine, the mainstay treatment in FMF, does not improve the axial or peripheral symptoms due t...
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Results In 14 of the 26 patients, FMF and amyloidosis were diagnosed at the same time with a mean delay in diagnosis of 22 ±9.2 years. In the remaining 12, there was a mean delay of 9.6±8 years from the onset to the diagnosis of FMF and 23±9.6 years from the onset to the diagnosis of amyloidosis. These patients were on colchicine for a mean of 13±7.6 years after the diagnosis of FMF. Eight were...
متن کاملP01-002 – Comparison between different colchicines responders
Results The study group comprised 221 FMF patients (116F, 105M) with a mean age of 12.7±5.3 years. Mean duration of colchicine use was 58.9±45.3 months. Patients were divided into two groups according to their colchicine response; Group I (n=131) included patients with no attacks after colchicine and Group II (n=90) patients with partial or no response to colchicine. Mean age, sex, age at disea...
متن کاملP01-031 – Anakinra for colchicine resistant FMF
Methods We plan to include patients, agreeing with clinical and genetic diagnosis of FMF, who suffer from FMF attacks, at least once per month, in one of the sites commonly involved by FMF (Chest, abdomen, lower extremity large joints, and skin), despite treatment with colchicine 2 mg/ day or less (in case of colchicine intolerance). Involvement with other diseases relevant (vasculitis, spondyl...
متن کاملP01-015 – Effect of Cochicine on cholesterol in FMF and BS
Introduction We and others have previously shown that patients with Familial Mediterranean Fever (FMF) had low cholesterol levels when compared to healthy controls [1,2]. This was initially brought up by Ozkan E [3]. The causes of this abnormality are not understood. It could be due to an inherent effect of FMF or due to a lipid lowering effect of colchicine, as the patients in these studies we...
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